NephPath 101 – Understanding the tubulointerstitium. – by NSMC2019 intern and nephro-pathologist Vighnesh Walavalkar.
Check out the original post on Renal Fellow Network
The tubulointerstitium of the kidney is broadly divided into the cortex and the medulla. These are extremely important components of the kidney, which can show a broad spectrum of changes ranging from subtle to significant, in both acute and chronic kidney injury. Therefore, in order to recognize the pathologic changes in these areas, one must first be familiar with its normal architecture
In this post, we will cover the main histologic features of the normal tubulointerstitium as seen on diagnostic kidney biopsies. For a more in-depth review please refer to my favorite references for kidney pathology: Heptinstall’s Pathology of the Kidney, Silva’s Diagnostic Renal Pathology and Renal Pathophysiology, The Essentials.